研发管线


我们创新的研发管线

科望医药基于消除肿瘤微环境中的免疫抑制因子,以及重新激活衰竭的T细胞这两大研发策略,建立起下一代肿瘤免疫疗法的创新产品管线,其中6款候选药物已进入临床研究阶段。


Asset
Target
Indications
Discovery
Preclinical
Ph1
Ph2
Ph3
Partner
ES104
VEGF/DLL4
  • BTC, CRC, OC

ES102
OX40
  • NSCLC, HNSCC

ES014
CD39/TGF-β
  • Solid Tumors
ES009
LILRB2
  • Solid Tumors
ES002
CD39
  • Solid Tumors
ES004
SIRPα
  • Solid Tumors
ES019 (BiME®)
SIRPα/PD-L1
  • SoIid Tumors

Other BiME® Programs
SIRPα/TAA
  • Solid Tumors
  • ES104
    View More
    Target
    VEGF/DLL4
    Discovery Preclinical Ph1 Ph2 Ph3
    +chemo
  • ES102
    View More
    Target
    OX40
    Discovery Preclinical Ph1 Ph2 Ph3
    +PD-1
  • ES014
    View More
    Target
    CD39/TGF-β
    Discovery Preclinical Ph1 Ph2 Ph3
    Monotherapy/+chemo/+IOs
  • ES009
    View More
    Target
    LILRB2
    Discovery Preclinical Ph1 Ph2 Ph3
    +PD-1
  • ES002
    View More
    Target
    CD39
    Discovery Preclinical Ph1 Ph2 Ph3
    Combo
  • ES004
    View More
    Target
    SIRPα
    Discovery Preclinical Ph1 Ph2 Ph3
    Combo
  • ES019 (BiME®)
    View More
    Target
    SIRPα/PD-L1
    Discovery Preclinical Ph1 Ph2 Ph3
    Monotherapy/Combo
  • Other BiME® Programs
    View More
    Target
    SIRPα/TAA
    Discovery Preclinical Ph1 Ph2 Ph3
    Monotherapy/Combo